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Side Effects
02 Jul 2025
118
1
Play free Side Effects - 3D Games
Side Effects is a chilling blend of horror and strategy that puts you in a psychological and tactical duel where every choice can mean survival or death. You play as one of two test subjects in a sinister facility, forced to swallow mysterious pills in alternating turns with an opponent. Some pills help, others harm, but the real question is: can you outwit death and your rival?
At its core, Side Effects plays like a strategic game of Russian roulette with pharmaceuticals. Each turn, you or your AI-controlled opponent must consume a pill or activate one of two chosen tools. These tools can protect you or sabotage your rival, such as a Mouth Clamp to force them to take a pill or a Drug Test to preview a pill's effect. The tension escalates each round, with pills becoming more unpredictable and side effects more dangerous.
Luck plays a role, but strategy is crucial. Not all pills are deadly; some may increase your health or even reset your poison levels, tracked on a meter connected to your body. But with every turn, the uncertainty grows. Reading the poison meter frequently and using tools wisely could mean the difference between winning or succumbing to a horrific fate.
The horror element is not just in the eerie setting or unsettling visuals, it’s in the psychological warfare. The game slowly builds dread, not through jump scares, but through the pressure of decisions, unknown consequences, and the slow realization that your opponent might be outmaneuvering you.
If you enjoyed Buckshot Roulette for its intensity and strategy, Side Effects offers a similar thrill, replacing bullets with experimental drugs and guns with medical tools. It’s a game of mind games, probability, and survival, all wrapped in a deeply atmospheric experience. Try it if you dare, but remember: in this lab, every choice could be your last.
How to play
Use the mouse.
